发明名称 LTB4 synthesis inhibitors
摘要 This invention relates to a compound of the formula <IMAGE> or a pharmaceutically acceptable salt thereof wherein X is oxygen, sulfur, -CH=CH-or -CH=N-; wherein R1 is alkyl, alkenyl or alkynyl of about 1 to 20 carbon atoms; wherein R is -CO2R2, tetrazole, methylsulfonamide or benzenesulfonamide, wherein R2 is hydrogen, alkyl of 1 to 6 carbon atoms or a pharmaceutically acceptable cation and R3 is hydroxyl or halogen, having utility as LTB4 synthesis inhibitors.
申请公布号 US5217981(A) 申请公布日期 1993.06.08
申请号 US19920967296 申请日期 1992.10.27
申请人 G. D. SEARLE & CO. 发明人 DJURIC, STEVAN W.;HAACK, RICHARD A.;MIYASHIRO, JULIE M.
分类号 C07C59/70;C07C59/74;C07C65/19;C07C65/30;C07C65/38;C07C311/51;C07D213/79;C07D257/04;C07D307/68;C07D333/38 主分类号 C07C59/70
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