摘要 |
This invention relates to a compound of the formula <IMAGE> or a pharmaceutically acceptable salt thereof wherein X is oxygen, sulfur, -CH=CH-or -CH=N-; wherein R1 is alkyl, alkenyl or alkynyl of about 1 to 20 carbon atoms; wherein R is -CO2R2, tetrazole, methylsulfonamide or benzenesulfonamide, wherein R2 is hydrogen, alkyl of 1 to 6 carbon atoms or a pharmaceutically acceptable cation and R3 is hydroxyl or halogen, having utility as LTB4 synthesis inhibitors.
|