PENTAPEPTIDE EXHIBITING SPECIFIC INHIBITION EFFECT IN EPIDERMAL CELL PROLIFERATION, ITS SALT, MEDICINE COMPOSITION CONTAINING THEM, AND THEIR PREPARATION

摘要

The present invention relates to novel pentapeptide of formula pAad-Glu-Asp-Ser-Gly-OH, wherein pAad represents the acyl group of pyro-alpha-aminoadipic acid, and salts thereof having specific inhibiting effect on epidermal cell proliferation, and pharmaceutical compositions comprising the same. The invention also relates to a process for the preparation of both the pentapeptide and the pharmaceutical composition.