发明名称 Aromatic carboxamides
摘要 Compounds of the general formula <IMAGE> I wherein R1 is hydrogen, halogen or OR5; R2 is hydrogen, lower-alkyl lower-alkoxy or halogen; R3 and R4 each independently are lower-alkyl or taken together are alkylene with 3-5 C atoms in a straight-chain; R5 is hydrogen, acyl, lower-alkoxycarbonyl, lower-alkyl, amino-lower-alkyl, mono-alkylamino-lower-alkyl di-alkylamino-lower-alkyl or a N-containing 5-8-membered saturated or unsaturated monocyclic heterocyclic ring which is attached via a N atom to lower alkyl; and M signifies -CONH- or -NHCO-, which can be used as medicaments, e.g., for the treatment of neoplasms and dermatological indications of an inflammatory and allergic nature.
申请公布号 US5216153(A) 申请公布日期 1993.06.01
申请号 US19920852607 申请日期 1992.03.17
申请人 HOFFMANN-LA ROCHE INC. 发明人 KLAUS, MICHAEL;MOHR, PETER
分类号 C07C233/65;C07C233/66;C07C233/75;C07C235/56;C07D295/092;C07D521/00 主分类号 C07C233/65
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