| 发明名称 |
IMMUNOSTIMULATING GUANINE DERIVATIVES, COMPOSITIONS AND METHODS |
| 摘要 |
7,8-Disubstituted guanosine nucleoside derivatives are found to be potent immune response enhancing agents in human and animal cells. 7-Substituents are hydrocarbyl radicals having a length greater than ethyl and less than about decyl. 8Substituents are =O, =S, =Se and =NCN. Compositions and methods of use are also disclosed. 0731F, D-134M |
| 申请公布号 |
CA1318666(C) |
申请公布日期 |
1993.06.01 |
| 申请号 |
CA19890598700 |
申请日期 |
1989.05.04 |
| 申请人 |
SCRIPPS CLINIC AND RESEARCH FOUNDATION |
发明人 |
GOODMAN, MICHAEL;WEIGLE, WILLIAM;BELL, STANLEY;CHEN, ROBERT;ROBINS, ROLAND K.;HENNEN, WILLIAM J. |
| 分类号 |
C07D473/18;A61K31/52;A61K31/522;A61K31/70;A61K31/7042;A61K31/7052;A61K31/7076;A61K31/708;A61K39/39;A61P37/04;C07H19/16;C07H19/167 |
主分类号 |
C07D473/18 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
