Aminoalkoxyphenyl derivatives, process of preparation and compositions containing the same

摘要

The present invention relates to aminoalkoxyphenyl compounds of formula: <IMAGE> in which: B is selected from -S-, -SO- and -SO2-, R1 and R2, which are identical or different, are selected from hydrogen, methyl, ethyl and halogen, A is selected from a straight- or branched-alkylene radical having from 2 to 5 carbon atoms, a 2-hydroxypropylene radical, and a 2-(lower alkoxy) propylene radical, R3 is selected from C1-C8 alkyl and a radical of formula: -Alk-Ar in which Alk is selected from a single bond and a linear- or branched-alkylene radical having from 1 to 5 carbon atoms; and Ar is selected from pyridyl, phenyl, 2-3-methyleneoxyphenyl, 3,4-methylenedioxyphenyl and phenyl substituted with one or more substituents, which may be identical or different, selected from halogen atoms, C1-C8 alkyl groups and C1-C8 alkoxy groups, R4 is selected from hydrogen and C1-C8 alkyl, or R3 and R4, when taken together, denote a 1,4-tetra-methylene, 1,5-pentamethylene, 3-oxa-1,5-pentamethylene, 3-aza-1,5-pentamethylene, 3-methylaza-1,5-pentamethylene, 3-phenylaza-1,5-pentamethylene or -CH=CH-N=CH- radical, R is selected from hydrogen, C1-C8 alkyl, C3-C6, cycloalkyl, benzyl, phenyl optionally substituted with one or more substituents, which may be identical or different, selected from halogen, C1-C4 alkyl and C1-C4 alkoxy as well as a pharmaceutically acceptable salt thereof.