| 摘要 |
Described herein are compounds of the formula <IMAGE> I wherein R1 signifies hydrogen, lower-alkyl or a cation; R2 signifies hydrogen, lower-alkyl, lower-alkoxy or halogen; M signifies -CONH- or -NHCO-; X and Y are each independently selected from the group consisting of >CR3R4 and -CONR5-; Z signifies >CR6R7; R3, R4, R6 and R7 are each independently selected from the group consisting of hydrogen and lower-alkyl; R5 signifies alkyl; and n signifies 0, 1 or 2; provided that at least one of X or Y is -CONR5- which is bonded to the phenyl ring via the N atom. These compounds are useful in the treatment and prophylaxis of neoplasms, dermatoses and aging of the skin.
|
