发明名称 |
Angiotensin II motverkande imidazolderivat, deras framstaellning och deras terapeutiska anvaendning |
摘要 |
<p>Compounds of formula (I): <CHEM> [in which: R<1> is hydrogen, alkyl, cycloalkyl or alkanoyl; R<2> is a single bond, alkylene or alkylidene; R<3> and R<4> are each hydrogen or alkyl; R<6> is carboxy or tetrazol-5-yl; and X is oxygen or sulphur]; and pharmaceutically acceptable salts and esters thereof are AII antagonists and can be used for the treatment and prophylaxis of hypertension and cardiovascular diseases.</p> |
申请公布号 |
FI932492(A0) |
申请公布日期 |
1993.06.01 |
申请号 |
FI19930002492 |
申请日期 |
1993.06.01 |
申请人 |
SANKYO COMPANY LIMITED |
发明人 |
YANAGISAWA, HIROAKI;SHIMOJI, YASUO;AMEMIYA, YOSHIYA;KANAZAKI, TAKURO;KOIKE, HIROYUKI;SADA, TOSHIO |
分类号 |
A61K31/415;A61K31/41;A61K31/4164;A61K31/4174;A61P9/00;A61P9/12;A61P43/00;C07D233/00;C07D233/66;C07D233/90;C07D403/10;C07D405/12;C07D405/14;(IPC1-7):C07D |
主分类号 |
A61K31/415 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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