发明名称 |
NOVEL BENZOTHIOPHENE DERIVATIVE |
摘要 |
A benzothiophene derivative represented by general formula (I) or a salt thereof, which has an excellent antiestrogenic activity and is useful for treating breast cancer, endometrial cancer, endometriosis, mastopathy, and so forth. This compound is characterized in that the 2-position, i.e. substituent R<2>, of the benzothiophene ring is substituted by a halogen atom, a lower alkyl group, or a cycloalkyl or cycloalkenyl group which may be substituted by a lower alkyl, hydroxy, acyloxy or oxo. |
申请公布号 |
WO9310113(A1) |
申请公布日期 |
1993.05.27 |
申请号 |
WO1992JP01465 |
申请日期 |
1992.11.11 |
申请人 |
TEIKOKU HORMONE MFG. CO., LTD. |
发明人 |
KOIZUMI, NAOYUKI;TAKEGAWA, SHIGEHIRO;IWASHITA, SHIGEKI;KAWACHI, TOMOKO;MATSUI, TERUAKI;MIEDA, MAMORU;TAKAHASHI, HIROO;SAITO, TOMOYUKI |
分类号 |
A61K31/38;A61K31/381;A61K31/4025;A61K31/4433;A61K31/445;A61K31/4535;A61K31/47;A61K31/4725;A61P5/32;A61P13/02;A61P15/00;A61P35/00;C07D333/54;C07D333/56;C07D333/58;C07D333/62;C07D409/12 |
主分类号 |
A61K31/38 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|