摘要 |
<p>Compounds of formula (II) or acid addition salts thereof, wherein R1 is hydrogen, C¿1-6? alkyl or C1-4 alkyl substituted by halo or C1-4 alkoxy, R?2¿ is C¿1-4? alkyl or C1-4 alkyl substituted by halo or C1-4 alkoxy, R?3¿ is C¿1-4? alkyl or C1-4 alkyl substituted by halo or C1-4 alkoxy or (a) forms a C5-7 cycloalkyl or cycloalkenyl group and R?4¿ is hydrogen or C¿1-4? alkyl are described as useful medicaments in the treatment of cancer. Pharmaceutical compositions containing the compounds and their manufacture are also disclosed.</p> |