摘要 |
<p>A few nitro compound of formula (I), wherein R?1 and R2¿ are each lower alkyl or lower alkoxy(lower)-alkyl, or (a) is cyclized to form (b), X is -O-, -S- or -NH-, m is an integer 0 or 1, and R3 is carbamoyl, lower alkylcarbamoyl, lower alkanoyl, di-lower alkylaminosulfonyl, lower alkylsulfonyl, oxamoyl or a group of the formula: -(Y)¿n-R?4, wherein Y is -CO-, -SO¿2?-, -COCH2 or (c), n is an integer of 0 or 1, and R?4¿ is heterocyclic group which is optionally substituted with one or more substituents selected from lower alkyl, lower alkoxy, phenyl, carbamoyl, halogen, amino, lower alkylthio, hydroxy, lower alkylsulfonylamino and carbamoylmethyl, and pharmaceutically acceptable salt thereof, which are useful for vasodilator.</p> |