发明名称 |
DIAGNOSTISCHE PROBE ZUM NACHWEIS VON PRAEDISPOSITION FUER DIABETES TYP 1. |
摘要 |
<p>An oligonucleotide probe capable of specifically hybridizing with the gene sequence 3 min -GCGGGCRARGRGGGGGRGCAG-5 min or 5 min -CGCCCGATACACCCCCACGTC-3 min wherein A is adenine, C is cytosine, G is guanine, T is thymine, and R is thymine or uracil. The probe may include at least 15 sequential nucleotides selected from the sequence 5 min -GCCCGATACACCCCCACGT-3 min or 3 min -CGGGCRARGRGGGGGRGCA-5 min The probe may be labelled with a detectable marker, such as an enzyme or biotin, and may be supplied in a diagnostic kit in combination with: a substratum capable of adsorbing DNA or cells, a restriction enzyme, and/or a detergent.</p> |
申请公布号 |
DE3880434(D1) |
申请公布日期 |
1993.05.27 |
申请号 |
DE19883880434 |
申请日期 |
1988.10.28 |
申请人 |
VIRGINIA MASON RESEARCH CENTER, SEATTLE, WASH., US |
发明人 |
NEPOM, GERALD T., BAINBRIDGE ISLAND WASHINGTON 98110, US |
分类号 |
G01N33/50;A61B10/00;C12N15/09;C12Q1/68;(IPC1-7):C12Q1/68 |
主分类号 |
G01N33/50 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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