发明名称 |
IMMUNOADSORBENT COMBINATION AND ASSAY TO DETECT GROUP B STREPTOCOCCUS POLYSACCHARIDE ANTIGEN AND IMMUNOCONJUGATE TO RAISE ANTIBODIES TO THE ANTIGEN |
摘要 |
<p>Immunoadsorbent combinations for the detection and diagnosis of group B streptococcus polysaccharide antigen, comprising an insoluble carrier, a capture agent having an affinity for specifically binding to the trirhamnose epitope of group B streptococcus antigen and having the formula alpha -L-Rhap(1->2)- alpha -L-Rhap(1->2) alpha -Rhap-1- wherein Rhap is rhamnose, and an antigen marker agent having an affinity for binding to monorhamnose epitope of group B streptococcus polysaccharide antigen of formula alpha -L-Rhap-1- when the group B streptococcus polysaccharide is bound to the carrier. An immunoassay method test kit and polyclonal antibody are also described. <IMAGE></p> |
申请公布号 |
NZ242433(A) |
申请公布日期 |
1993.05.26 |
申请号 |
NZ19920242433 |
申请日期 |
1992.04.22 |
申请人 |
PRESIDENT & FELLOWS OF HARVARD COLLEGE;THE BRIGHAM & WOMEN'S HOSPITAL INC;NATIONAL RESEARCH COUNCIL OF CANADA |
发明人 |
JENNINGS, HAROLD J;MICHON, FRANCIS;CHALIFOUR, ROBERT J;LACROIX, MARTIAL;FELDMAN, ROBERT;KASPER, DENNIS L;POZSGAY, VINCE |
分类号 |
A61K39/395;A61K39/40;C07K14/00;C07K14/315;C07K16/00;C07K16/12;C07K19/00;C12P21/08;G01N33/53;G01N33/569;G01N33/577;(IPC1-7):A61K39/40;A61K31/71;A61K31/70;G01N33/543;C07K15/00;A61K39/44;C07K15/28 |
主分类号 |
A61K39/395 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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