COMPOSITIONS OF PATHOGEN-ASSOCIATED MOLECULAR PATTERNS AND METHODS OF USE

摘要

COMPOSITIONS COMPRISE AT LEAST A PORTION OF AN ANTIGEN AND AT LEAST A PORTION OF A FLAPELLIN THAT LACKS A HINGE REGION. COMPOSITIONS, FUSION PROTEINS AND POLYPEPTIDES COMPRISE AT LEAST A PORTION OF AT LEAST ONE PATHOGEN-ASSOCIATED I MOLECULAR PATTERN AND AT LEAST A PORTION OF AT LEAST ONE VIRAL PROTEIN. THE VIRAL PROTEIN OF THE COMPOSITIONS, FUSION PROTEINS AND POLYPEPTIDES OF THE INVENTION ARE FLAVIVIRAL PROTEINS, INCLUDING A WEST NILE FLAVIVIRAL PROTEIN, A DENGUE FLAVIVIRAL PROTEIN, A LANGAT FLAVIVIRAL PROTEIN, A KUNJIN FLAVIVIRAL PROTEIN, A MURRAY VALLEY ENCEPHALITIS FLAVIVIRAL PROTEIN, A JAPANESE ENCEPHALITIS FLAVIVIRAL PROTEIN. A TICK- BORNE ENCEPHALITIS FLAVIVIRAL PROTEIN, A YELLOW FEVER FLAVIVIRAL PROTEIN AND A HEPATITIS C FLAVIVIRAL PROTEIN. THE COMPOSITIONS, FUSION PROTEINS AND POLYPEPTIDES ARE USED TO STIMULATE AN IMMUNE) RESPONE IN A SUBJECT.