PHARMACEUTICAL COMPOSITIONS FOR ORAL USE AND METHOD OF PREPARING THEM

摘要

A pharmaceutical composition for oral use comprising an effective amount of a compound of the formula (I) having antagonistic action to angiotensin II (I) (wherein the ring W is an optionally substituted Ncontaining heterocyclic residue; R3 is a group capable of forming an anion or a group convertible thereinto; X is a direct bond or a spacer having an atomic length of two or less between the phenylene group and the phenyl group; and n is an integer of 1 or 2) and an oleaginous substance having a lower melting point, and a method for preparing a pharmaceutical composition for oral use comprising an effective amount of a compound of the formula (I) and an oleaginous substance having a lower melting point, which comprises admixing the compound of the formula (I) with an oleaginous substance having a lower melting point and then subjecting the mixture to molding.