发明名称 OXAZOLIDONE DERIVATIVE
摘要 An oxazolidone derivative represented by general formula (I) and having a monoamine oxidase inhibitory activity, a pharmacologically acceptable salt thereof, and a drug containing the same as the active ingredient for preventing or treating diseases for which a monoamine oxidase inhibitory activity is efficacious. In formula (I) A and B represent each nitrogen, sulfur or oxygen provided that either A or B represents nitrogen; R<1> represents a group of formula (a) wherein n and m represent each an integer of 0, 1 to 4; and R<3> and R<4> represent each hydrogen, hydroxy, lower alkyl, etc.; a group of formula (b) wherein p and q represent each an integer of 0, 1 to 4; and X represents oxygen, sulfur, etc., a group of formula (c) wherein R<5> and R<6> represent each hydrogen, cyanoalkyl, etc., or alternatively R<5> and R<6> are bonded to each other to represent a ring together with the nitrogen atom to which they are bonded; and so forth; R<2> represents hydrogen or lower alkyl; and the bond ---- represents either a single or a double bond. <CHEM>
申请公布号 AU2692792(A) 申请公布日期 1993.05.21
申请号 AU19920026927 申请日期 1992.09.30
申请人 EISAI CO., LTD. 发明人 KOZO AKASAKA;AKIHARU KAJIWARA;SATOSHI NAGATO;YOUICHI IIMURA;ICHIROU YOSHIDA;ATSUSHI SASAKI;MASANORI MIZUNO;ATSUHIKO KUBOTA;TAKAKI KAGAYA;MARIKO KOMATSU
分类号 A61K31/42;A61K31/423;A61K31/425;A61K31/445;A61P25/24;A61P25/26;C07D263/56;C07D263/57;C07D263/58;C07D417/04;C07D417/14 主分类号 A61K31/42
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