BIOCONTROL OF MICROBIAL PATHOGENS

摘要

Pseudomonas mutant strains which continue to secrete siderophores when iron is present in the growth environment are described. Such strains are suitable for use as biological agents to control microbial pathogens. Also described are DNA fragments containing sequences for iron-mediated regulation of siderophore production in Pseudomonas strains, plasmids containing such DNA fragments and methods of producing Pseudomonas strains deregulated for siderophore production. Also described are methods of controlling the growth of deleterious microorganisms by introducing siderophore onto an environment and maintaining the level thereof to inhibit growth of the microorganisms regardless of the iron concentration in the environment.