发明名称 AMORPHOUS (QUINOLIN-2-YLMETHOXY) INDOLES
摘要 A form of 3-[N-(p-chlorobenzyl)-3-(t-butylthio)-5-(quinolin-2-ylmethoxy)indol-2- yl]-2,2-dimethylpropanoic acid sodium salt, obtained by freeze or spray drying, is more soluble in water than the crystalline form thereof. The compound is useful as an anti-asthmatic, anti-allergic, anti-inflammatory, or cytoprotective agent. It is also useful in treating diarrhea, hypertension, angina, platelet aggregation, cerebral spasm, premature labor, spontaneous abortion, dysmenorrhea, and migraine.
申请公布号 AU2836292(A) 申请公布日期 1993.05.20
申请号 AU19920028362 申请日期 1992.11.13
申请人 MERCK FROSST CANADA, INC. 发明人 JOHN H. HUTCHINSON;BRIAN DOWN
分类号 A61K31/47;A61P11/00;A61P43/00;C07D401/12 主分类号 A61K31/47
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