发明名称 |
METHOD OF DETERMINING A SITE OF INFLAMMATION UTILIZING ELAM-1 LIGANDS |
摘要 |
Ligands in the form of N-acetyllactosamines which bind to endothelial leukocyte adhesion molecule-1 (ELAM-1) are disclosed. The ligand compounds can be formulated into pharmaceutical compositions and/or assay compositions used to alleviate inflammation and assay for the presence of (qualitative) and amount of (quantitative) ELAM-1 and thereby determine the presence, location and degree of inflammation.
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申请公布号 |
US5211937(A) |
申请公布日期 |
1993.05.18 |
申请号 |
US19910683458 |
申请日期 |
1991.04.11 |
申请人 |
GLYCOMED INCORPORATED |
发明人 |
BRANDLEY, BRIAN K.;TIEMEYER, MICHAEL;SWIEDLER, STUART J.;MORELAND, MARGARET;SCHWEINGRUBER, HANS |
分类号 |
A61K31/70;A61K31/7008;A61K31/7028;A61K47/36;A61K47/48;A61K49/00;A61K51/08;A61M5/32;A61P29/00;C07H5/04;C07H13/04;C07H15/10;C07K14/705;C08B37/00;G01N33/53;G01N33/569;G01N33/68 |
主分类号 |
A61K31/70 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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