| 摘要 |
<p>PURPOSE:To provide a system of widely alleviating side effects and improving safety and treating effects by utilizing an existing anticancer agent, especially an anticancer antibiotic and concentratedly transferring the anticancer agent to the target cancer cells. CONSTITUTION:An anticancer agent comprising an antibody-linked anticancer agent obtained by utilizing a partial peptide of an extracellular hydrophilic site in a protein amino acid sequence of cancer gene C-erbB-2 product as an antigen to give a monoclonal antibody, utilizing the monoclonal antibody as an antibody to recognize a membrane protein of adenocarcinoma cell and linking the antibody to adriamycin, as an active ingredient. This anticancer agent effectively acts on adenocarcinoma cell, especially cancer cells to yield product of cancer gene C-erbB-2.</p> |
