QUINUCLIDINE COMPOUND AND MEDICINAL USE THEREOF

摘要

A quinuclidine compound represented by general formula (I) and a pharmaceutically acceptable acid addition salt thereof, wherein each symbol is as defined in the specification. Because they have a P substance antagonism, they are useful for treating pains such as migraine, inflammations, respiratory system diseases such as chronic bronchitis accompanied with cough, sputum, etc., asthma, or rhinitis, central nervous system diseases such as anxiety or psychosis, cardiovascular system diseases such as hypertension or heart failure, and digestive system diseases such as hypersensitive colitis, ulcerous colitis or Crohn disease.