发明名称 |
Immunization against Babesiosis using purified merozoite surface antigens of Basesia bigemina |
摘要 |
Antigenic surface proteins from the intraerythrocytic merozoite stage of Babesia bigemina have been isolated using cell fusions and monoclonal antibodies produced thereby. Immunization of mammals, such as bovines, with purified isolates induces an immunological response that is effective to reduce pathological effects of babesiosis induced by Babesia bigemina. Diagnostic kits using monoclonal antibodies and antigenic surface proteins of Babesia bigemina are also disclosed.
|
申请公布号 |
US5209929(A) |
申请公布日期 |
1993.05.11 |
申请号 |
US19910663255 |
申请日期 |
1991.03.01 |
申请人 |
WASHINGTON STATE UNIVERSITY RESEARCH FOUNDATION |
发明人 |
MCGUIRE, TRAVIS;MCELWAIN, TERRY;PERRYMAN, LANCE;DAVIS, WILLIAM |
分类号 |
A61K39/00;C07K14/44 |
主分类号 |
A61K39/00 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|