PRODUCTION OF CARBOXYLIC ACID ESTER

摘要

PURPOSE:To prevent the yield of the subject compound from deteriorating due to saponifying reaction and avoid deterioration in operating efficiency due to foaming by carrying out esterifying reaction in the presence of an acidic catalyst and then neutralizing acidic substances in the reactional solution with a specific neutralizing agent. CONSTITUTION:An aliphatic carboxylic acid and/or its anhydride (preferably 1-6C acid and/or its anhydride such as acetic acid) and an alcohol (preferably a phenoxy-based alcohol such as 1-phenoxy-2-propanol) are initially subjected to esterifying reaction in the presence of an acidic catalyst (preferably p- toluenesulfonic acid) to afford a carboxylic acid ester. Acidic substances present in the reactional solution containing the produced carboxylic acid ester are then neutralized with an aqueous solution containing an alkali metallic hydroxide and an alkali metallic carbonate as a neutralizing agent, preferably at <=80 deg.C temperature. Furthermore, the alkali metallic hydroxide and the alkali metallic carbonate are preferably mixed at 1:(0.25-8) equiv. ratio.