发明名称 METHODS AND REAGENTS FOR HLA CLASS 1 DNA TYPING
摘要 Primers for amplification of specific nucleic acid sequences of the second and third exon of HLA Class I genes and probes for identifying polymorphic sequences contained in the amplified DNA can be used in processes for typing homozygous or heterozygous samples from a variety of sources and for detecting allelic variants not distinguishable by serological methods. This HLA Class I DNA typing system can be used in a forward or reverse dot-blot format that is simple and rapid to perform, produces detectable signals in minutes, and can-be used for tissue typing, determining individual identity, and identifying disease susceptible individuals.
申请公布号 AU2748592(A) 申请公布日期 1993.05.06
申请号 AU19920027485 申请日期 1992.11.02
申请人 F.HOFFMANN-LA ROCHE AG 发明人 TEODORICA BUGAWAN;HENRY A. ERLICH
分类号 G01N33/50;C07H21/04;C12N15/09;C12Q1/68 主分类号 G01N33/50
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