ANTITUMOR 6-SULFENAMIDE, 6-SULFINAMIDE AND 6-SULFONAMIDE PURINES, PURINE NUCLEOSIDES, PURINE NUCLEOTIDES AND RELATED COMPOUNDS

摘要

wherein R1 and R2 independently are H, OH, -O-acyl or O= , or together R1 and R2 are O= , and R3 and R4 are, H or one of R3 or R4 is OH and the other is H; provided that when Y is H, Z is -NH2; and acceptable salt thereof are prepared and are useful as antitumor agents or they are intermediates for compounds which are antitumor agents. The compounds are used to treat an affected warm blooded host by serving as the active ingredients of suitable pharmaceutical compositions.