| 摘要 |
PCT No. PCT/SE92/00724 Sec. 371 Date Jun. 21, 1994 Sec. 102(e) Date Jun. 21, 1994 PCT Filed Oct. 16, 1992 PCT Pub. No. WO93/07860 PCT Pub. Date Apr. 29, 1993The invention relates to the use of, and methods to obtain, ion exchanger complexes with psychotropic drugs for reducing toxic side effects and lethality when overdosing the drug. The invention includes methods and compositions for modifying the total amount of drug released from the complex in the gastro-intestinal tract by adding a substance which affects the ion exchange process. The additional substance may be a salt which generates an ion with higher or similar affinity to the ion exchanger when compared to the drug. The additional substance may be a counter ion in an additional complex with an ion exchanger. |
