摘要 |
<p>Pharmaceutically useful nitrogen containing cyclic oxime substituted compounds which are arylacetylene and arylenyne azabicyclo [2.2.1] oximes of formula (I) which are useful for alleviating pain and for treating cognitive decline are described; pharmaceutical compositions and a method of manufacture are also described. In formula (I), R is selected from the group (IIa) and (IIb).</p> |