| 摘要 |
<p>A method and apparatus for determining non-invasively the presence and/or concentration of blood analytes such as glucose in an animal, particularly a human animal. The apparatus comprises a light source (1) for producing a polychromatic light beam and means (4) for modulating the polychromatic light beam such that the modulation frequency is dependent upon the wavelength of light within the beam. The modulated light beam is caused to impinge upon a body part, preferably the front surface (10) of the eye of the animal so that blood analytes interact with the light beam and perturb the spectral distribution of light within the beam. Spectral information is extracted from the resulting light beam by detecting the beam at a plurality of modulation frequencies. The measurements may be linked to pulse measurements in a manner similar to pulse oximetry. The light beam may also be used to heat the body part to a desired temperature. A moulding (23) locates the light source and detector in a fixed location with respect to facial features of the animal. Various methods, including the use of polarisers and CCD detector arrays, are proposed to minimise the effect of specular reflection.</p> |
