摘要 |
<p>The progression of neurodegenerative diseases is hindered by inhibiting lysosomal enzymes. Such enzymes may be inhibited outside the cell or inside the lysosome, for example with enzyme inhibitors such as bestatin or with antibodies directed to the enzyme(s). Active immunisation of the patient may be used to raise such antibodies in situ. Alternatively, the pH of the lysosome may be raised.</p> |