| 发明名称 |
NONPEPTIDYL INTEGRIN INHIBITORS HAVING SPECIFICITY FOR GPIIBIIIA RECEPTOR |
| 摘要 |
2119745 9308174 PCTABScor01 A benzodiazepinedione derivative which acts as a nonpeptidyl platelet aggregation inhibitor is provided. This inhibitor potently inhibits fibrinogen binding to the GPIIbIIIa receptor and is provided in therapeutic compositions for the treatment of diseases for which blocking platelet aggregation is indicated. These nonpeptidyl inhibitors are provided in combination with thrombolytics and anticoagulants.
|
| 申请公布号 |
CA2119745(A1) |
申请公布日期 |
1993.04.29 |
| 申请号 |
CA19922119745 |
申请日期 |
1992.10.15 |
| 申请人 |
GENENTECH INC |
发明人 |
BLACKBURN BRENT;BARKER PETER;GADEK THOMAS;MCDOWELL ROBERT;MCGEE LAWRENCE;SOMERS TODD;WEBB ROB;ROBARGE KIRK |
| 分类号 |
A61K31/55;A61K31/551;A61K31/5513;A61K31/5517;A61K31/553;A61P7/02;A61P43/00;C07D223/16;C07D243/10;C07D243/14;C07D267/14;C07D401/06;C07D401/12;(IPC1-7):C07D243/10;C07D403/02;C07D413/02;C07D417/02;C07D487/04;C07D405/12;C07F9/547;A61K31/675 |
主分类号 |
A61K31/55 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
