| 摘要 |
<p>Methods for administering drugs transdermally via diffusion from a transdermal drug delivery device (10) wherein the device (10) is applied to the skin and the device (10) and skin underlying the device (10) are heated by applying an external source of heat to the device or by instigating an exothermic reaction within the device to cause the skin temperature to increase to a temperature below 45 °C and thereby cause a thermal enhancement of the flux of drug through the skin. A top layer (12) is a conductive layer that serves as a backing, for conducting heat to layer (13). Layer (12) is an adhesive polymer permeable to the drug. A release layer (14) is removed prior to use.</p> |
