发明名称 |
PRODUCTION OF FUCOSYLATED CARBOHYDRATES BY ENZYMATIC FUCOSYLATION SYNTHESIS OF SUGAR NUCLEOTIDES; AND IN SITU REGENERATION OF GDP-FUCOSE |
摘要 |
This invention contemplates improved methods of enzymatic production of carbohydrates especially fucosylated carbohydrates. Improved syntheses of glycosyl 1- or 2-phosphates using both chemical and enzymatic means are also contemplated. The phosphorylated glycosides are then used to produce sugar nucleotides that are in turn used as donor sugars for glycosylation of acceptor carbohydrates. Especially preferred herein in the use of a disclosed method for fucosylation. |
申请公布号 |
WO9308205(A1) |
申请公布日期 |
1993.04.29 |
申请号 |
WO1992US08789 |
申请日期 |
1992.10.15 |
申请人 |
THE SCRIPPS RESEARCH INSTITUTE |
发明人 |
WONG, CHI-HUEY;ICHIKAWA, YOSHITAKA;SHEN, GWO-JENN;LIU, KUN-CHIN |
分类号 |
C12P19/02;C07H3/06;C07H5/02;C07H11/04;C07H13/04;C07H13/08;C07H15/18;C07H19/04;C07H19/10;C07H19/20;C12P19/18;C12P19/26;C12P19/30 |
主分类号 |
C12P19/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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