| 摘要 |
<p>An instrument (22) and methods of making and use for sealing a small opening, e.g., percutaneous incisions or punctures (28). The instrument (22) includes a tubular member (30) having a proximal portion (34) and a distal portion (32) with an open free end (36) for introduction into the incision or puncture (28). A plug (20) comprises a cord (50) and a thin filament (52), with the cord (50) being formed of a resorbable material and being folded in two to form an apex portion (64) and a pair of wing portions (66A, 68A) extending therefrom. The plug (20) is located within the tubular member (30) so that the apex portion (64) is disposed adjacent the free end. The plug (20) is then expelled partially from the tubular member (30) so that the apex portion (64) extends through the incision or puncture (28). The filament (52) is then drawn proximally to pull the apex portion (64) into engagement with the free end of the tubular member to expand the apex portion to form a head (68) having a tissue engagement surface.</p> |
