发明名称 |
METHOD FOR PRODUCING ANTIGENE SPECIFICAL HUMAN MONOCLONAL ANTIBODIES OF HIGH AFFINITY |
摘要 |
The present invention relates to advances in monoclonal antibody production, and particularly, in culturing methodology preparatory to hybridoma formation. Specifically, retention of lymphoid fragments in the culture systems results in predominantly IgG-secreting, long-lived cultures. |
申请公布号 |
HU9203635(D0) |
申请公布日期 |
1993.04.28 |
申请号 |
HU19920003635 |
申请日期 |
1991.05.21 |
申请人 |
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA,US |
发明人 |
BOERNER,PAULA,US;ROYSTON,YVOR,US |
分类号 |
A61K39/395;A61K38/00;C07K16/00;C07K16/18;C07K16/42;C12N5/00;C12N5/02;C12N5/06;C12N5/10;C12N5/16;C12N5/24;C12N15/02;C12P21/08;C12R1/91 |
主分类号 |
A61K39/395 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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