发明名称 6-OXO-AZEPINOINDOL COMPOUNDS AS WELL AS A PROCESS AND INTERMEDIATE PRODUCTS FOR THE PRODUCTION THEREOF,AND DRUGS THAT CONTAIN THESE COMPOUNDS
摘要 Pharmacologically active compounds corresponding to the general formula I <IMAGE> I in which R1 represents hydrogen, a lower alkyl or cycloalkyl-alkyl group or an optionally substituted phenyl-lower alkyl group, R2 denotes hydrogen or a lower alkyl group optionally substituted in the alpha -position to the nitrogen atom by lower alkoxy, R3 denotes hydrogen, lower alkyl, lower alkoxy, halogen or hydroxyl, n represents 1 or, if the -(CH2)n- chain is in the 4-position of the ring structure, also represents 2, R4 denotes hydrogen, lower alkyl, cycloalkyl, cycloalkyl-lower alkyl or an optionally substituted phenyl-lower alkyl group, and R5 denotes hydrogen, lower alkyl, cycloalkyl, cycloalkyl-lower alkyl or an optionally substituted phenyl-lower alkyl group, or R4 and R5, together with the nitrogen atom to which they are bonded, form a heterocycle and D represents a bond, or, if R4 and R5 do not denote hydrogen, also represents the -N=CH- group, and their physiologically acceptable acid addition salts are described, and also processes and intermediates for their preparation.
申请公布号 ZA9205093(B) 申请公布日期 1993.04.28
申请号 ZA19920005093 申请日期 1992.07.08
申请人 KALI-CHEMIE PHARMA GMBH. 发明人 WERNER BENSON;KARIN VAN CHARLDORP;PETER COLIN GREGORY;KLAUS-ULLRICH WOLF;ULF PREUSCHOFF;MARTIN TULP;TON HULKENBERG;INEKE VAN WIJNGAARDEN
分类号 A61K31/55;A61K31/40;A61K31/407;A61P1/00;A61P1/14;A61P25/04;A61P25/06;A61P43/00;C07D209/10;C07D487/04;C07D487/06 主分类号 A61K31/55
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