发明名称 |
PROCESS FOR THE PREPARATION OF SUBSTITUTED BENZOFURAN DERIVATIVES |
摘要 |
The present invention relates to a process for the preparation of a compound of the following formula (I) <CHEM> wherein one of R1 and R2 is hydrogen or halogen and the other is independently, an amino group or a C2-C4 alkanoyl amino group; R3 is hydrogen; a linear or branched alkyl, C1-C4 alkoxy or C2-C4 alkoxycarbonyl group; halogen; or phenyl unsubstituted or substituted by a C1-C4 alkyl group; A is a group -(CH2)n-Het wherein Het is an optionally substituted heteromonocyclic or heterobicyclic ring containing one or two nitrogen atoms and n is zero or an integer of 1 to 3; and the symbol .... represents a single or double bond and the pharmaceutically acceptable salts thereof. The compounds of the invention can be useful as 5HT3 receptor antagonists. |
申请公布号 |
ZA9110125(B) |
申请公布日期 |
1993.04.28 |
申请号 |
ZA19910010125 |
申请日期 |
1991.12.23 |
申请人 |
FARMITALIA CARLO ERBA S.R.L. |
发明人 |
ANGELO BEDESCHI;WALTER CABRI;ILARIA CANDIANI;SILVIA DE BERNARDINIS;MARCELLO MARCHI |
分类号 |
C07D307/84;A61K31/34;A61K31/343;C07D307/79;C07D307/83;C07D405/12;C07D451/04;C07D451/14;C07D453/02;C07D453/06;C07D455/02;C07D471/08 |
主分类号 |
C07D307/84 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|