DEVICE COATED WITH PROTEIN NONABSORBING POLYUREA-URETHANE POLYMER

摘要

PURPOSE: To provide a medical and laboratory device which is coated with a polymer characterized by adaptability to vital organism and a resistance against non-peculiar protein adsorption. CONSTITUTION: A device according to the invention is coated with prepolymers whose terminals are capped with a high molecular weight isocyanate consisting of ethylene oxide unit sustantially or exclusively. The portion at least 75%, preferably over 90%, of the prepolymer unit should be diols or polyols including oxyethylene as radicals having a molecular weight of approx. 7000-30,000 where substantially all hydroxyl groups are capped with polyisocyanate prior to the manufacture of a hydrated polymer coating.