Maytansinoids, their production and therapeutic compositions containing them.

摘要

Novelmaytansinoidcompoundsoftheformula:
<Chemistry id="chema01" num="0001"><Image id="ia01" he="42" wi="68" file="IMGA0001.TIF" imgContent="chem" imgFormat="TIFF" inline="no" /></Chemistry>wherein X is H or Cl, R<Sup>1</Sup> is an alkyl group of 2 to 4 carbon atoms and R<Sup>2</Sup> is a lower alkyl group or an unsubstituted or substituted phenyl or aralkyl group, have antimitotic, antitumor and antimicrobial activities.