摘要 |
39-21(2662)A PROCESS FOR THE PREPARATION OF N-HYDROXYALKYL- N-PHOSPHONOMETHYLGLYCINE An efficient process is disclosed for the preparation of N-(2-hydroxyalkyl)-N-phosphonomethyl-glycine represented by the formula <IMG> which comprises heating, preferably to reflux, an aqueous solution of glyoxal and N-(2-hydroxyalkyl)amino-methylphosphonic acid represented by the formula <IMG> wherein R and R1 are individually hydrogen, an alkyl having 1 to 4 carbon atoms, or aryl. Preferably both R and R1 are hydrogen.
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