Taste mask coatings for preparing chewable pharmaceutical tablets.

摘要

Chewable medicament tablets are made from coated rotogranules of a medicament wherein the rotogranules are formed from a granulation mixture of: medicament, e.g. famotidine; binder, e.g. HPMC; and carrier, e.g. lactose; and the rotogranules are coated with cellulose acetate, cellulose acetate butyrate or a combination thereof and hydroxypropyl cellulose. A process for making such tablets and a method of providing taste masking of medicaments utilizing such coated rotogranules.