| 摘要 |
PURPOSE:To efficiently obtain D-serine in high purity by allowing a microbial cell having tyrosinase activity to act on a reaction liquid containing DL-serine and phenol and converting only L-serine into L-tyrosine. CONSTITUTION:A microorganismic cell having tyrosinase activity [preferably Escherichia coil TD-001 (FERM P-10838)] or treated product thereof is made to act on a reaction liquid containing DL-serine and phenol to convert L-serine into L-tyrosine and then unreacted D-serine is collected. The reaction is preferably carried out in a solvent such as 0.1M phosphoric acid buffer solution at 30-40 deg.C, normally for 2-72hr. |
