| 摘要 |
<p>This invention relates to regulation of G protein functions and the related axonal growth. The invention further relates to the discovery that GAP-43 and palmitoylated GAP-43 and biologically active peptides derived therefrom function to modulate cell function. The present invention also is related to the clinical in vivo and in vitro diagnostic and therapeutic applications of GAP-43 and palmitoylated GAP-43 and their regulatory and membrane-targeting elements. Also disclosed is a method of palmitoylating the GAP-43 protein.</p> |
