| 摘要 |
PCT No. PCT/US91/00007 Sec. 371 Date Jun. 25, 1992 Sec. 102(e) Date Jun. 25, 1992 PCT Filed Jan. 4, 1991 PCT Pub. No. WO91/10684 PCT Pub. Date Jul. 25, 1991.Biologically active oxidized variants of granulocyte-macrophage colony stimulating factor (GM-CSF) are provided in which one or more methionine residues are oxidized. Methods are also provided for making and characterizing such variants. |
