PREPARATION AND USE OF HUMAN TROPHOBLAST MEMBRANE EXPRESSED PROTEIN IN AN ANTI-FERTILITY VACCINE

摘要

An anti-fertility vaccine capable of stimulating the production of antibodies which prevent or inhibit pregnancy in a female animal, including a woman, comprises human trophoblast membrane expressed protein, or an immunologically-active fragment thereof, as active immunogen. Preparation of human trophoblast membrane expressed protein in substantially pure form from human placentas by conventional protein purification means or by recombinant DNA technology is also disclosed.