Use of formesyl-protein transferase inhibitors for the manufacture of a medicament for blocking neoplastic transformation of cells induced by ras oncogenes.

摘要

A method is provided by blocking or preventing the prenylation of CAAX box containing proteins including ras oncogene products thereby preventing and/or treating ras-related tumors which includes the step of administering a therapeutically effective amount of a protein-prenyl transferase inhibitor.