发明名称 Menetelmä terapeuttisesti aktiivisten tetratsolijohdannaisten valmistamiseksi
摘要 The invention relates to a process for the preparation of tetrazole derivatives, which are antihypercholesterolaemic agents, of the formula IIa or IIb <IMAGE> <IMAGE> wherein R1 and R4 are hydrogen, halogen, C1-4 alkyl, C1-4 alkoxy or trifluoromethyl; R2, R3, R5 and R6 are hydrogen, halogen, C1-4 alkyl or C1-4 alkoxy; and R7 is hydrogen, a hydrolyzing ester group or pharmaceutically acceptable cation. The invention relates further to tetrazole derivatives, which are useful intermediates for the preparation of the compounds of the formula IIa or IIb, and to the process for the preparation thereof.
申请公布号 FI931580(A) 申请公布日期 1993.04.07
申请号 FI19930001580 申请日期 1993.04.07
申请人 BRISTOL-MYERS SQUIBB COMPANY 发明人 WRIGHT, JOHN J.;SIT, SING-YUEN;BALASUBRAMANIAN, NEELAKANTAN;BROWN, PETER J.
分类号 C07D257/04;C07D405/06;C07F9/6524 主分类号 C07D257/04
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