发明名称 QUINAZOLINE DERIVATIVES AND THEIR PREPARATION
摘要 A compound of formula (I) in which R<1> is substituted heterocyclic-(lower)alkyl, and R<2> is hydrogen, halogen, nitro, amino, protected amino, hydroxyamino, lower alkyl, hydroxy, protected hydroxy, sulfamoyl, carboxy, protected carboxy, mercapto, optionally substituted heterocyclic-carbonyl, optionally substituted heterocyclic-(lower)alkyl, lower alkylthio, hydroxy(lower)alkyl or protected hydroxy(lower)alkyl, R<3> is aryl which may have suitable substituent(s), and A is lower alkylene, or pharmaceutically acceptable salts thereof, useful as a dopamine receptor agonist, 5-HT receptor antagonist or alpha 1 receptor antagonist.
申请公布号 AU2500992(A) 申请公布日期 1993.04.05
申请号 AU19920025009 申请日期 1992.09.02
申请人 FUJISAWA PHARMACEUTICAL CO., LTD. 发明人 NORIHIKO SHIMAZAKI;YOSHIKUNI ITOH;TAKUMI YATABE;HITOSHI YAMAZAKI;MASASHI HASHIMOTO;HIROKAZU TANAKA
分类号 A61K31/505;A61P43/00;C07D401/06;C07D401/14 主分类号 A61K31/505
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