发明名称 TRIAZOLYLATED TERTIARY AMINE COMPOUND OR SALT THEREOF
摘要 A triazolylated tertiary amine compound represented by general formula (I) or a salt thereof, having an aromatase inhibitory activity and being useful for preventing and treating breast cancer, mastopathy, endometriosis, prostatomegaly, etc., wherein A represents a single bond, lower alkylene or carbonyl; B represents lower alkyl, aryl, a 5- or 6- membered heterocyclic group, or a bicyclic fused heterocyclic group; D represents aryl, a 5- or 6-membered heterocyclic group, or a bicyclic fused heterocyclic group; and E represents 4H-1,2,4-triazolyl, 1H-1,2,4-triazolyl or 1H-1,2,3-triazolyl. <CHEM>
申请公布号 AU2487492(A) 申请公布日期 1993.04.05
申请号 AU19920024874 申请日期 1992.08.27
申请人 YAMANOUCHI PHARMACEUTICAL CO., LTD. 发明人 MINORU OKADA;EIJI KAWAMINAMI;TORU YODEN;MASAFUMI KUDO;YASUO ISOMURA
分类号 A61K31/425;A61P35/00;C07D249/04;C07D249/08;C07D401/12;C07D403/12;C07D521/00;C12N9/00 主分类号 A61K31/425
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