摘要 |
<p>This invention relates to pyrrolobenzoxazine derivatives represented by formula (I), wherein R1 is hydrogen, etc., R?2 and R3¿ are each lower alkyl, etc., R4 is azabicyclo(C¿5?-C12)alkyl which may be substituted with lower alkyl, etc., R?5¿ is halogen, etc., X is α, etc., A is lower alkylene and n is an integer of 0 or 1. The object compounds and pharmaceutically acceptable salt thereof have pharmacological activities such as 5-HT antagonism and agonism.</p> |