发明名称 |
PYRIMIDINE NUCLEOSIDE DERIVATIVES HAVING ANTI-TUMOR ACTIVITY, THEIR PREPARATION AND USE |
摘要 |
Compounds of formula (I): (I) wherein: R1, R2 and R3 are independently selected from the group consisting of hydrogen atoms, optionally substituted alkanoyl groups and alkenylcarbonyl groups, PROVIDED THAT at least one of R1, R2 and R3 represents an unsubstituted alkanoyl group having from 5 to 24 carbon atoms, said substituted alkanoyl group or said alkenylcarbonyl group; and one of R4 and R5 represents a hydrogen atom and the other represents a cyano group; have valuable anti-tumor activity.
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申请公布号 |
CA2079413(A1) |
申请公布日期 |
1993.03.31 |
申请号 |
CA19922079413 |
申请日期 |
1992.09.29 |
申请人 |
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发明人 |
KANEKO, MASAKATSU;KOBAYASHI, TOMOWO;HOTODA, HITOSHI;SHIBATA, TOMOYUKI;MITSUHASHI, YOSHIHIRO;MATSUDA, AKIRA;SASAKI, TAKUMA |
分类号 |
A61K31/505;A61K31/70;A61K31/7042;A61K31/7052;A61K31/7064;A61K31/7068;A61P35/00;C07D405/04;C07H19/06;C07H19/073;C07H19/09;(IPC1-7):C07H19/09;C07H23/00 |
主分类号 |
A61K31/505 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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