THE USE OF CERTAIN SALTS OF MEDETOMIDINE AND ITS OPTICALLY ACTIVE ENANTIOMERS TO REGULATE THE RATE OF TRANSDERMAL ADMINISTRATION OF THE DRUGS

摘要

Salts of medetomidine and optically active enantiomers, thereof, particularly the d-enantiomer are disclosed. These salts may be used to regulate the rate of the transdermal administration of active drugs. The transdermal delivery system comprises a drug impermeable backing layer and an adhesive layer wherein the medetomidine is dispersed throughout the adhesive layer.